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Image Search Results
Journal: Cell reports
Article Title: Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products
doi: 10.1016/j.celrep.2019.10.042
Figure Lengend Snippet:
Article Snippet: Flow cytometry antibodies used included: Live/Dead fixable aqua dead cell stain (Invivogen) (1:500 dilution), BV786 Anti-mouse CD4 (BD Clone RM4–5) (1:200 dilution, APC Anti-mouse IFNγ (eBiosciences Clone XMG1.2) (1:200 dilution),
Techniques: Recombinant, Purification, Activity Assay, In Situ, Enzyme-linked Immunosorbent Assay, Bicinchoninic Acid Protein Assay, Staining, RNA Sequencing Assay, Sequencing, Software, SYBR Green Assay, Protease Inhibitor, Cell Counting
Journal: Viruses
Article Title: Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry
doi: 10.3390/v11020176
Figure Lengend Snippet: In vivo activity of Tyrphostin A9, Monensin, and Sofosbuvir. ( A ) Schematic of the drug treatment and infection regime in AG129 mice. Mice were treated with 5.7 mg/kg of Sofosbuvir, 10 mg/kg of Monensin, or 1mg/kg of Tyrphostin A9 before and after infection with 10 5 pfu of ZIKV, at the indicated intervals. Administration of Tyrphostin A9 was suspended at day 3 due to toxicity. Focus-forming units (ffu, top panels) and ZIKV RNA copies (bottom panels) per ml of serum at day 1, 3, and 7 p.i. upon treatment with Sofosbuvir ( B ), Monensin ( C ), or Tyrphostin A9 ( D ). N.D. (not detected), indicates that no infectious units were recovered. ZIKV RNA copies/ng at day 7 p.i. in the lymph nodes ( E ), liver ( F ), and brain ( G ) upon indicated treatment. Percentages of CD14 + CD11b + macrophages ( H ), CD14 + CD11c + DC ( I ), and CD3 + CD4 + T cells ( J ) infected with ZIKV at day 7 p.i. upon indicated treatment. P values from unpaired T tests are displayed for statistically significant comparisons.
Article Snippet: PE-Cy7 rat anti-mouse CD11b,
Techniques: In Vivo, Activity Assay, Infection